Biologist
CAMRIS

Job Info

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Overview

We are seeking a Biologist to support the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a team focused on positively impacting millions of lives around the world. Candidates will work at a diverse and vibrant NIAID worksite to directly support ongoing research activities as a contractor team member. Take the next big step in your career and apply below to help us make a difference.

CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.

Our employees enjoy a diverse, collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities

• Perform a broad range of tasks related to evaluating vaccine efficacy in a nonhuman primate (NHP) model of Mycobacterium tuberculosis (TB).
• Conduct research independently including planning experiments, writing animal protocols, data generation, analysis, and interpretation.
• Perform various immunological assays on cells from NHP blood and tissue related to the evaluation of experimental TB vaccines: flow cytometry, cell sorting, confocal microscopy, RNA extraction, Luminex, ELISA.
• Monitor supplies and equipment maintenance at BSL2 and BSL3 level-lab space.
• Monitor NHP sample inventories to include shipping and receiving samples to and from collaborators.
• Perform duties related to BSL-3 TB vaccine studies in nonhuman primates at an off-site location (Bioqual Inc., 2501 Research Blvd, Rockville, MD 20850) and maintain compliance with all training requirements of this non-NIH facility.
• Develop, implement, and monitor compliance of a BSL-3 Safety Manual for tuberculosis vaccine studies in nonhuman primates.
• Develop BSL3-level standard operating procedures (SOPs) for monitoring immune responses and measuring protective efficacy after vaccination and challenge with TB, including accurately quantifying mycobacterial burdens from animal tissues.
• Interact with pre-doctoral and post-doctoral fellows, and research technicians to provide agent specific training, lab-specific training, and standardization of BSL-3 protocols.
• Assist in identifying and onboarding new research technician candidates for BSL3 lab work.
• Develop new (BSL3) assays to assess anti-mycobacterial activity from NHP cells ex vivo following vaccination (i.e., in vitro growth assays).
• Prepare data abstracts, posters, and presentations to clearly communicate data to Scientific colleagues in the form of internal scientific meetings.
• Participate in finalizing data, preparing figures, authoring text, and preparing overall manuscripts for timely publication of data.

Qualifications

• Master's degree in Immunology, Microbiology, or related field.
• Minimum of four (4) years of technical experience working within a BSL-3 laboratory on the nonhuman primate model of Mycobacterium tuberculosis.
• Extensive experience isolating immune cells from animal or human blood and tissues.
• Extensive experience culturing and quantifying Mtb from infected animal tissues.
• Ability to effectively train and oversee others on BSL-3 laboratory technique to comply with all safety regulations.
• Experience evaluating antigen-specific cellular immune responses using multi-parameter flow cytometry, Luminex, ELISA.
• Understanding of nonhuman primate or human T cell immunology as it relates to vaccine efficacy.
• Demonstrated expertise in flow cytometry data analysis using FlowJo.
• Computer skills to include MS Office Suite, GraphPad Prism.
• Organization and written/verbal communication skills as to prepare written protocols, contribute to publications and communicate data to others.

CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at www.CAMRIS.com . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

Some positions or sites may require that the incumbent be fully vaccinated against COVID-19. Proof of vaccination may be required.

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.

This job has expired.